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产品简介
英文名称 | Anti-JUP Polyclonal Antibody |
靶标 | JUP |
别名 | CTNNG, DP3 |
宿主 | Rabbit |
稀释比例 | WB 1:1000-3000. IHC 1:50-200. |
Gene ID | 3728 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | P14923 |
蛋白分子量 | 82kDa |
储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
亚细胞定位 | Cytoplasm Cell membrane |
免疫原 | Recombinant protein of human JUP |
亚型 | IgG |
纯化方法 | Affinity purification |
背景资料 | Common junctional plaque protein. The membrane-associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of plakoglobin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. Acts as a substrate for VE-PTP and is required by it to stimulate VE-cadherin function in endothelial cells. Can replace beta-catenin in E-cadherin/catenin adhesion complexes which are proposed to couple cadherins to the actin cytoskeleton. |
Public Immunogen Range | 396-746aa |
克隆类型 | Polyclonal Antibody |
交叉反应 | HumanRatMouse |
应用 | WBIHC |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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