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产品简介
| 英文名称 | Anti-NDFIP1 Polyclonal Antibody |
| 靶标 | NDFIP1 |
| 别名 | N4WBP5, NDFIP1, PSEC0223 |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:200-1000.IF 1:20-200.IP 0.5-4.0 ug for IP and 1:200-1:1000 for WB. |
| Gene ID | 80762 |
| 保存 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
| Swiss Prot | Q9BT67 |
| 蛋白分子量 | 25 kDa |
| 储存液 | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| 亚细胞定位 | Secreted |
| 免疫原 | Fusion protein of human NDFIP1 |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | Ndfip1 is an adaptor protein for the Nedd4 family of ubiquitin ligases and has been found to be upregulated in neurons after brain injury, including head trauma, stroke and metal toxicity. Recent studies confirmed the role of Ndfip1 as a regulator of iron metabolism and pointed out that Ndfip1 was involved in iron homeostasis by regulating the degradation of iron importer divalent metal transporter 1. Ndfip1 is a transmembrane protein that is localized to the Golgi and post-Golgi vesicles such as endosomes. It is an adaptor protein that recruits E3 ligases to ubiquitinate target proteins. It is ubiquitously expressed and contains 2 PY motifs, which interact with several Nedd4 family E3s to degradate proteins. |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | HumanRatMouse |
| 应用 | WBELISAIPIF |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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