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产品简介
靶标 | CAPN6 |
别名 | CANPX; CAPNX; CalpM; DJ914P14.1 |
宿主 | Rabbit |
稀释比例 | WB 1:500-2000. IHC 1:50-100 |
Gene ID | 827 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | Q9Y6Q1 |
蛋白分子量 | 75 kDa |
储存液 | pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
亚细胞定位 | Cytoplasm |
免疫原 | Fusion protein of human CAPN6 |
亚型 | IgG |
纯化方法 | Antigen affinity purification |
背景资料 | Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this gene is highly expressed in the placenta. Its C-terminal region lacks any homology to the calmodulin-like domain of other calpains. The protein lacks critical active site residues and thus is suggested to be proteolytically inactive. The protein may play a role in tumor formation by inhibiting apoptosis and promoting angiogenesis. |
克隆类型 | Polyclonal Antibody |
交叉反应 | HumanRatMouse |
应用 | WBELISAIHC |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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