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产品简介
靶标 | TAF11 |
别名 | TAF2I; PRO2134; TAFII28; MGC:15243 |
宿主 | Rabbit |
稀释比例 | WB 1:500-2000. IHC 1:35-150 |
Gene ID | 6882 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | Q15544 |
蛋白分子量 | 23 kDa |
储存液 | pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
亚细胞定位 | Cytoplasm |
免疫原 | Fusion protein of human TAF11 |
亚型 | IgG |
纯化方法 | Antigen affinity purification |
背景资料 | Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a small subunit of TFIID that is present in all TFIID complexes and interacts with TBP. This subunit also interacts with another small subunit, TAF13, to form a heterodimer with a structure similar to the histone core structure. Two transcript variants encoding different isoforms have been found for this gene. |
克隆类型 | Polyclonal Antibody |
交叉反应 | HumanRatMouse |
应用 | WBELISAIHC |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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