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产品简介
| 靶标 | SORBS2 |
| 别名 | ARGBP2; PRO0618 |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:1000-5000. IHC 1:150-300 |
| Gene ID | 8470 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | O94875 |
| 蛋白分子量 | 124 kDa |
| 储存液 | pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| 亚细胞定位 | Cytoplasm |
| 免疫原 | Fusion protein of human SORBS2 |
| 亚型 | IgG |
| 纯化方法 | Antigen affinity purification |
| 背景资料 | Arg and c-Abl represent the mammalian members of the Abelson family of non-receptor protein-tyrosine kinases. They interact with the Arg/Abl binding proteins via the SH3 domains present in the carboxy end of the latter group of proteins. This gene encodes the sorbin and SH3 domain containing 2 protein. It has three C-terminal SH3 domains and an N-terminal sorbin homology (SoHo) domain that interacts with lipid raft proteins. The subcellular localization of this protein in epithelial and cardiac muscle cells suggests that it functions as an adapter protein to assemble signaling complexes in stress fibers, and that it is a potential link between Abl family kinases and the actin cytoskeleton. Alternative splicing results in multiple transcript variants encoding different isoforms. |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | HumanRatMouse |
| 应用 | WBELISAIHC |
| 规格 | 50ul100ul |
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1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
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