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产品简介
| 靶标 | GAPDH |
| 别名 | GAPDH |
| 宿主 | Mouse |
| 稀释比例 | WB 1:2000-5000.IF 1:100-200. |
| Swiss Prot | P04406 |
| 蛋白分子量 | 36kDa |
| 亚细胞定位 | Cytoskeleton Cytosol Nucleus |
| 免疫原 | Recombinant Protein |
| 亚型 | IgG1 |
| 纯化方法 | Affinity purification |
| 背景资料 | Glyceraldehyde 3 phosphate dehydrogenase (GAPDH) is well known as one of the key enzymes involved in glycolysis. As well as functioning as a glycolytic enzyme in cytoplasm, recent evidence suggests that mammalian GAPDH is also involved in a great number of intracellular proceses such as membrane fusion, microtubule bundling, phosphotransferase activity, nuclear RNA export, DNA replication, and DNA repair. During the last decade a lot of data appeared concerning the role of GAPDH in different pathologies including prostate cancer progression, programmed neuronal cell death, age related neuronal diseases, such as Alzheimer's and Huntington's disease. GAPDH is expressed in all cells. It is constitutively expressed in almost all tissues at high levels. There are however some physiological factors such as hypoxia and diabetes that increase GAPDH expression in certain cell types. GAPDH molecule is composed of four 36kDa subunits. |
| 克隆类型 | Monoclonal Antibody |
| 交叉反应 | HumanRatMouse |
| 应用 | WBIF |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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