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产品简介
靶标 | RASSF7 |
别名 | C11orf13; Chromosome 11 open reading frame 13; HRAS1; HRAS1 related cluster 1; HRAS1 related cluster protein 1; HRAS1-related cluster protein 1; HRC1; MGC126069; MGC126070; Ras association (RalGDS/AF 6) domain family (N terminal) member 7; Ras association (RalGDS/AF 6) domain family 7; Ras association domain containing protein 7; Ras association domain-containing protein 7; RASF7_HUMAN; RASSF 7; RASSF7; |
宿主 | Rabbit |
稀释比例 | WB 1:1000-3000. |
Gene ID | 8045 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | Q02833 |
蛋白分子量 | 35/36/40kDa |
储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
亚细胞定位 | Cytoplasm |
免疫原 | A synthetic peptide of human RASSF7 |
亚型 | IgG |
纯化方法 | Affinity purification |
背景资料 | Negatively regulates stress-induced JNK activation and apoptosis by promoting MAP2K7 phosphorylation and inhibiting its ability to activate JNK. Following prolonged stress, anti-apoptotic effect stops because of degradation of RASSF7 protein via the ubiquitin-proteasome pathway. Required for the activation of AURKB and chromosomal congression during mitosis where it stimulates microtubule polymerization. |
Public Immunogen Range | 323-373/373 |
克隆类型 | Polyclonal Antibody |
交叉反应 | Human |
应用 | WB |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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