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产品简介
靶标 | HDAC3 |
别名 | HD3;RPD3;RPD3-2 |
宿主 | Rabbit |
稀释比例 | WB 1:1000-3000. |
Gene ID | 8841 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | O15379 |
蛋白分子量 | 49kDa |
储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
亚细胞定位 | Nucleus Cytoplasm |
免疫原 | A synthetic peptide of human HDAC3 |
亚型 | IgG |
纯化方法 | Affinity purification |
背景资料 | Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. |
Public Immunogen Range | 300-350/428 |
克隆类型 | Polyclonal Antibody |
交叉反应 | HumanPredicted:Chicken Chimpanzee Zebrafish Xenopus laevis Xenopus tropicalis FishRatMouse |
应用 | WB |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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