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产品简介
靶标 | MRTFA |
别名 | AI852829; AMKL; AW743281; AW821984; Basic SAP coiled-coil transcription activator; Bsac; KIAA1438; Mal; Megakaryoblastic leukemia 1 protein; Megakaryocytic acute leukemia protein; MKL (megakaryoblastic leukemia)/myocardin like 1; MKL/myocardin like protein 1; MKL/myocardin-like protein 1; Mkl1; MKL1_HUMAN; MRTF A; Mrtf A; MRTF-A; MRTFA; MYOCARDIN RELATED PROTEIN; Myocardin related transcription factor A; Myocardin-related transcription factor A; |
宿主 | Rabbit |
稀释比例 | WB 1:1000-3000. |
Gene ID | 57591 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | Q969V6 |
蛋白分子量 | 99kDa |
储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
亚细胞定位 | Cytoplasm Nucleus |
免疫原 | A synthetic peptide of human MRTFA |
亚型 | IgG |
纯化方法 | Octanoic acid-ammonium sulfate precipitation |
背景资料 | Transcription coactivator that associates with the serum response factor (SRF) transcription factor to control expression of genes regulating the cytoskeleton during development, morphogenesis and cell migration. The SRF-MRTFA complex activity responds to Rho GTPase-induced changes in cellular globular actin (G-actin) concentration, thereby coupling cytoskeletal gene expression to cytoskeletal dynamics. MRTFA binds G-actin via its RPEL repeats, regulating activity of the MRTFA-SRF complex. Activity is also regulated by filamentous actin (F-actin) in the nucleus. |
Public Immunogen Range | 755-805/931 |
克隆类型 | Polyclonal Antibody |
交叉反应 | HumanMouse |
应用 | WB |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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