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产品简介
| 靶标 | DHRS2 |
| 别名 | 5430405K24Rik; Dehydrogenase/reductase (SDR family) member 2; Dehydrogenase/reductase member 2; Dehydrogenase/reductase SDR family member 2; Dehydrogenase/reductase SDR family member 2 mitochondria; Dicarbonyl reductase HEP27; Hep27; HEP27 protein; MGC143467; Protein D; SDR family member; SDR25C1; Short chain alcohol dehydrogenase family member; Short chain dehydrogenase/reductase family 25C member 1; |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:1000-3000. |
| Gene ID | 10202 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | Q13268 |
| 蛋白分子量 | 30/31kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 亚细胞定位 | Cytoplasm Nucleus |
| 免疫原 | A synthetic peptide of human DHRS2 |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | Displays NADPH-dependent dicarbonyl reductase activity in vitro with 3,4-Hexanedione, 2,3-Heptanedione and 1-Phenyl-1,2-propanedione as substrates. No reductase activity is displayed in vitro with steroids, retinoids and sugars as substrates. Attenuates MDM2-mediated p53/TP53 degradation, leading to p53/TP53 stabilization and increased transcription activity, resulting in the accumulation of MDM2 and CDKN1A/p21. |
| Public Immunogen Range | 175-225/280 |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | Human |
| 应用 | WB |
| 规格 | 50ul100ul |
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