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产品简介
| 靶标 | NOLC1 |
| 别名 | 140 kDa nucleolar phosphoprotein; HCV NS5A trans regulated protein 13; HCV NS5A transactivated protein 13; HCV NS5A-transactivated protein 13; Hepatitis C virus NS5A transactivated protein 13; Hepatitis C virus NS5A-transactivated protein 13; KIAA0035; NOLC 1; NOLC1; NOLC1_HUMAN; NOPP 130; NOPP 140; NOPP130; Nopp140; NS5ATP13; Nucleolar 130 kDa protein; Nucleolar and coiled body phosphoprotein 1; Nucleolar and coiled body phosphprotein 1; Nucleolar and coiled-body phosphoprotein 1; Nucleolar phosphoprotein p130; Nucleolar protein p130; P130; |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:2000-5000. IHC 1:25-100. |
| Gene ID | 9221 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | Q14978 |
| 蛋白分子量 | 74/75kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 亚细胞定位 | Nucleus Cytoplasm |
| 免疫原 | A synthetic peptide of human NOLC1 |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | Nucleolar protein that acts as a regulator of RNA polymerase I by connecting RNA polymerase I with enzymes responsible for ribosomal processing and modification (PubMed:10567578, PubMed:26399832). Required for neural crest specification: following monoubiquitination by the BCR(KBTBD8) complex, associates with TCOF1 and acts as a platform to connect RNA polymerase I with enzymes responsible for ribosomal processing and modification, leading to remodel the translational program of differentiating cells in favor of neural crest specification (PubMed:26399832). Involved in nucleologenesis, possibly by playing a role in the maintenance of the fundamental structure of the fibrillar center and dense fibrillar component in the nucleolus (PubMed:9016786). It has intrinsic GTPase and ATPase activities (PubMed:9016786). |
| Public Immunogen Range | 610-660/699 |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | HumanRatMouse |
| 应用 | WBIHC |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
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