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产品简介
靶标 | BLOC1S2 |
别名 | BLOS2;BORCS2;CEAP;CEAP11 |
宿主 | Rabbit |
稀释比例 | IHC 1:50-200. |
Gene ID | 282991 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | Q6QNY1 |
蛋白分子量 | 11/16kDa |
储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
亚细胞定位 | Cytoplasm |
免疫原 | Recombinant protein of human BLOC1S2 |
亚型 | IgG |
纯化方法 | Affinity purification |
背景资料 | Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes (PubMed:15102850, PubMed:17182842). In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension (By similarity). As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor (PubMed:25898167). May play a role in cell proliferation (PubMed:15381421). |
Public Immunogen Range | 1-99aa |
克隆类型 | Polyclonal Antibody |
交叉反应 | HumanRatMouse |
应用 | IHC |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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