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产品简介
靶标 | ARNT2 |
别名 | ARNT2;WEDAS;bHLHe1 |
宿主 | Rabbit |
稀释比例 | IHC 1:50-200. |
Gene ID | 9915 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | Q9HBZ2 |
蛋白分子量 | 78/79kDa |
储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
亚细胞定位 | Nucleus Cytoplasm |
免疫原 | Recombinant protein of human ARNT2 |
亚型 | IgG |
纯化方法 | Octanoic acid-ammonium sulfate precipitation |
背景资料 | This gene encodes a member of the basic-helix-loop-helix-Per-Arnt-Sim (bHLH-PAS) superfamily of transcription factors. The encoded protein acts as a partner for several sensor proteins of the bHLH-PAS family, forming heterodimers with the sensor proteins that bind regulatory DNA sequences in genes responsive to developmental and environmental stimuli. Under hypoxic conditions, the encoded protein complexes with hypoxia-inducible factor 1alpha in the nucleus and this complex binds to hypoxia-responsive elements in enhancers and promoters of oxygen-responsive genes. A highly similar protein in mouse forms functional complexes with both aryl hydrocarbon receptors and Single-minded proteins, suggesting additional roles for the encoded protein in the metabolism of xenobiotic compounds and the regulation of neurogenesis, respectively. |
Public Immunogen Range | 1-350aa |
克隆类型 | Polyclonal Antibody |
交叉反应 | HumanRatMouse |
应用 | IHC |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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