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产品简介
| 靶标 | PTPN2 |
| 别名 | PTPN2;PTN2;PTPT;TC-PTP;TCELLPTP;TCPTP |
| 宿主 | Rabbit |
| 稀释比例 | IHC 1:50-200. |
| Gene ID | 5771 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | P17706 |
| 蛋白分子量 | 40/45/48kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 亚细胞定位 | Cytoplasm Nucleus |
| 免疫原 | A synthetic peptide of human PTPN2 |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Epidermal growth factor receptor and the adaptor protein Shc were reported to be substrates of this PTP, which suggested the roles in growth factor mediated cell signaling. Multiple alternatively spliced transcript variants encoding different isoforms have been found. Two highly related but distinctly processed pseudogenes that localize to chromosomes 1 and 13, respectively, have been reported. |
| Public Immunogen Range | 165-215/415 |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | HumanPredicted: ChickenRatMouse |
| 应用 | IHC |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
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