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产品简介
| 靶标 | STAM2 |
| 别名 | DKFZp564C047;Hbp;Hrs-binding protein;HSE1 homolog;Signal transducing adapter molecule 2;Signal transducing adaptor molecule (SH3 domain and ITAM motif) 2;Signal transducing adaptor molecule 2A;Signal transducing adaptor molecule 2B;Signal transducing adaptor molecule;STAM like protein containing SH3 and ITAM domains 2;STAM-2;Stam2;STAM2_HUMAN;STAM2A;STAM2B |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:1000-3000.;IHC 1:50-200. |
| Gene ID | 10254 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | O75886 |
| 蛋白分子量 | 38/58kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.4. |
| 亚细胞定位 | Cytoplasm Nucleus |
| 免疫原 | A synthetic peptide of human STAM2 |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | Involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and MYC induction. May also play a role in T-cell development. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with HGS (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes (By similarity). |
| Public Immunogen Range | 180-230/525aa |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | Human |
| 应用 | WB;IHC |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
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