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产品简介
| 靶标 | CCP110 |
| 别名 | 110 kDa centrosomal protein;CCP110;Centriolar coiled coil protein 110kDa;Centrosomal protein 110 kDa;Centrosomal protein CP110;Centrosomal protein of 110 kDa;Cep110;CP110 |
| 宿主 | Rabbit |
| 稀释比例 | IHC 1:100-300. |
| Gene ID | 9738 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | O43303 |
| 蛋白分子量 | 113kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.4. |
| 亚细胞定位 | Cytoplasm |
| 免疫原 | A synthetic peptide of human CCP110 |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | Necessary for centrosome duplication at different stages of procentriole formation. Acts as a key negative regulator of ciliogenesis in collaboration with CEP97 by capping the mother centriole thereby preventing cilia formation (PubMed:17719545 PubMed:17681131, PubMed:23486064). Also involved in promoting ciliogenesis. May play a role in the assembly of the mother centriole subdistal appendages (SDA) thereby effecting the fusion of recycling endosomes to basal bodies during cilia formation (By similarity). Required for correct spindle formation and has a role in regulating cytokinesis and genome stability via cooperation with CALM1 and CETN2 (PubMed:16760425). |
| Public Immunogen Range | 135-185/1012aa |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | Human |
| 应用 | IHC |
| 规格 | 50ul100ul |
注意：
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