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产品简介
| 靶标 | STAT5B |
| 别名 | STAT 5; STAT 5A; STAT5; STAT5A; Signal transducer and activator of transcription 5B; STA5B_HUMAN; STAT5; Stat5b |
| 宿主 | Rabbit |
| 预测交叉反应 | Cow;Pig |
| 稀释比例 | IHC 1:50-200. |
| Gene ID | 6777 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | P51692 |
| 蛋白分子量 | 90kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 亚细胞定位 | Cytoplasm Nucleus |
| 免疫原 | A synthetic peptide of human STAT5B |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL. [provided by RefSeq, Jul 2008] |
| Public Immunogen Range | 737-787/787aa |
| 克隆类型 | Polyclonal Antibody |
| 应用 | IHC |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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