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产品简介
宿主 | Rabbit |
稀释比例 | IHC 1:25-100. |
Gene ID | 9125 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | Q92600 |
蛋白分子量 | 29/34/37kDa |
储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
亚细胞定位 | Cytoplasm |
免疫原 | A synthetic peptide of human CNOT9 |
亚型 | IgG |
纯化方法 | Affinity purification |
Important Note | Important Note |
背景资料 | Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Involved in down-regulation of MYB- and JUN-dependent transcription. May play a role in cell differentiation (By similarity). Can bind oligonucleotides, such as poly-G, poly-C or poly-T (in vitro), but the physiological relevance of this is not certain. Does not bind poly-A. Enhances ligand-dependent transcriptional activity of nuclear hormone receptors, including RARA, expect ESR1-mediated transcription that is not only slightly increased, if at all. |
Public Immunogen Range | 30-80/299aa |
克隆类型 | Polyclonal Antibody |
交叉反应 | HumanRatMouse |
应用 | IHC |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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