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产品简介
宿主 | Rabbit |
稀释比例 | IHC 1:25-100. |
Gene ID | 9454 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | Q9NSC5 |
蛋白分子量 | 14/36/40kDa |
储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
亚细胞定位 | Cytoplasm |
免疫原 | A synthetic peptide of human HOMER3 |
亚型 | IgG |
纯化方法 | Affinity purification |
Important Note | Important Note |
背景资料 | Postsynaptic density scaffolding protein. Binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. By physically linking GRM1 and GRM5 with ER-associated ITPR1 receptors, it aids the coupling of surface receptors to intracellular calcium release. Isoforms can be differently regulated and may play an important role in maintaining the plasticity at glutamatergic synapses. Negatively regulates T cell activation by inhibiting the calcineurin-NFAT pathway. Acts by competing with calcineurin/PPP3CA for NFAT protein binding, hence preventing NFAT activation by PPP3CA. |
Public Immunogen Range | 5-55/361aa |
克隆类型 | Polyclonal Antibody |
交叉反应 | HumanRatMouse |
应用 | IHC |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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