暂无数据
产品名称
起订量
单价(含增值税)
库存(PCS)
起订数量
产品简介
宿主 | Rabbit |
稀释比例 | WB 1:500-2000. IP 0.5-4.0 ug for IP and 1:500-1000 for WB. IHC 1:50-500. IF1:50-500. |
Gene ID | 142 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | P09874 |
蛋白分子量 | 113 kDa |
储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
亚细胞定位 | Chromosome Nucleus |
免疫原 | PARP1 fusion protein |
亚型 | IgG |
纯化方法 | Affinity purification |
Important Note | Important Note |
背景资料 | PARP1 (poly(ADP-ribose) polymerase 1) is a nuclear enzyme catalyzing the poly(ADP-ribosyl)ation of many key proteins in vivo. The normal function of PARP1 is the routine repair of DNA damage. Activated by DNA strand breaks, the PARP1 is cleaved into an 85 to 89-kDa COOH-terminal fragment and a 24-kDa NH2-terminal peptide by caspases during the apoptotic process. The appearance of PARP fragments is commonly considered as an important biomarker of apoptosis. In addition to caspases, other proteases like calpains, cathepsins, granzymes and matrix metalloproteinases (MMPs) have also been reported to cleave PARP1 and gave rise to fragments ranging from 42-89-kDa. This antibody was generated against the C-terminal region of human PARP1 and it recognizes the full-length as well as the cleavage of the PARP1. |
克隆类型 | Polyclonal Antibody |
交叉反应 | HumanPigRatMouse |
应用 | WBELISAIFIHCIP |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
暂无数据
我要询价
*联系方式:
(可以是QQ、MSN、电子邮箱、电话等,您的联系方式不会被公开)
*内容: