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产品简介
英文名称 | Anti-CDH2 Polyclonal Antibody |
靶标 | CDH2 |
别名 | Cadherin-2;CDw325;Neural cadherin;N-cadherin;CD325;CDHN;NCAD |
宿主 | Rabbit |
预测交叉反应 | Cow;Chimpanzee;Chicken;Monkey |
稀释比例 | WB 1:1000-3000. |
Gene ID | 1000 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | P19022 |
蛋白分子量 | 97/100kDa |
储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
亚细胞定位 | Cell membrane |
免疫原 | A synthetic peptide of human CDH2 |
亚型 | IgG |
纯化方法 | Affinity purification |
背景资料 | Calcium-dependent cell adhesion protein; preferentially mediates homotypic cell-cell adhesion by dimerization with a CDH2 chain from another cell. Cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence. Plays a role in cell-to-cell junction formation between pancreatic beta cells and neural crest stem (NCS) cells, promoting the formation of processes by NCS cells (By similarity). CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density. |
Public Immunogen Range | 800-850/906aa |
克隆类型 | Polyclonal Antibody |
应用 | WB |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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