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产品简介
| 英文名称 | Anti-GRIA4 Polyclonal Antibody |
| 靶标 | GRIA4 |
| 别名 | GluR-4;GluR4;Glutamate receptor 4;GluR-D;GluA4;GLUR4 |
| 宿主 | Rabbit |
| 预测交叉反应 | Monkey |
| 稀释比例 | WB 1:1000-3000. |
| Gene ID | 2893 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | P48058 |
| 蛋白分子量 | 49/101kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 亚细胞定位 | Cell membrane |
| 免疫原 | A synthetic peptide of human GRIA4 |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate. |
| Public Immunogen Range | 375-425/902aa |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | Human;Mouse;Rat |
| 应用 | WB |
| 规格 | 50ul100ul |
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