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产品简介
| 英文名称 | Anti-Ikaros(C-term) Monoclonal Antibody |
| 别名 | CVID13;Hs.54452;IK1;IKAROS;LyF-1;LYF1;PPP1R92;PRO0758;ZNFN1A1 |
| 宿主 | Mouse |
| 稀释比例 | WB 1:1000. |
| Gene ID | 10320 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | Q13422 |
| 蛋白分子量 | 58kDa |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 亚细胞定位 | Cytoplasm Nucleus Nucleus |
| 免疫原 | Purified recombinant human IKZF1(C-terminus) protein fragments expressed in E.coli. |
| 亚型 | IgG1 |
| 性状 | 液体 |
| 纯化方法 | Affinity purification |
| 克隆号 | 1A12-F2-D8 |
| 背景资料 | Transcription regulator of hematopoietic cell differentiation. Binds gamma-satellite DNA. Binds with higher affinity to gamma satellite A. Plays a role in the development of lymphocytes, B- and T-cells. Binds and activates the enhancer (delta-A element) of the CD3-delta gene. Repressor of the TDT (terminal deoxynucleotidyltransferase) gene during thymocyte differentiation. Regulates transcription through association with both HDAC-dependent and HDAC-independent complexes. Targets the 2 chromatin-remodeling complexes, NuRD and BAF (SWI/SNF), in a single complex (PYR complex), to the beta-globin locus in adult erythrocytes. Increases normal apoptosis in adult erythroid cells. Confers early temporal competence to retinal progenitor cells (RPCs). |
| 克隆类型 | Monoclonal Antibody |
| 交叉反应 | Human |
| 应用 | WBIP |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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