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产品简介
| 英文名称 | Anti-CDK4 Monoclonal Antibody |
| 别名 | CDK4;Cell division protein kinase 4;CMM3;cyclin dependent kinase 4;PSK-J3 |
| 宿主 | Mouse |
| 稀释比例 | WB 1:1000. |
| Gene ID | 1019 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | P11802 |
| 蛋白分子量 | 33kDa |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 亚细胞定位 | Cytoplasm Membrane Nucleus |
| 免疫原 | Purified recombinant human CDK4 protein fragments expressed in E.coli. |
| 亚型 | IgG1 |
| 性状 | 液体 |
| 纯化方法 | Affinity purification |
| 克隆号 | 3F9-B12-C8 |
| 背景资料 | The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression. The activity of this kinase is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16(INK4a). This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product (Rb). Mutations in this gene as well as in its related proteins including D-type cyclins, p16(INK4a) and Rb were all found to be associated with tumorigenesis of a variety of cancers. Multiple polyadenylation sites of this gene have been reported. |
| Public Immunogen Range | Purified recombinant human CDK4 protein fragments expressed in E.coli. |
| 克隆类型 | Monoclonal Antibody |
| 交叉反应 | HumanRatMouse |
| 应用 | WB |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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