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产品简介
| 英文名称 | Anti-HDAC3 Monoclonal Antibody |
| 别名 | HD3;RPD3-2;SMAP45;Histone deacetylase 3;RPD3 |
| 宿主 | Mouse |
| 稀释比例 | WB 1:1000. |
| Gene ID | 8841 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | O15379 |
| 蛋白分子量 | 49kDa |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 亚细胞定位 | Cytoplasm Nucleus cytosol |
| 免疫原 | Purified recombinant human HDAC3 protein fragments expressed in E.coli. |
| 亚型 | IgG1 |
| 性状 | 液体 |
| 纯化方法 | Affinity purification |
| 克隆号 | 3G3-H6-H10 |
| 背景资料 | Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. |
| Public Immunogen Range | Purified recombinant human HDAC3 protein fragments expressed in E.coli. |
| 克隆类型 | Monoclonal Antibody |
| 交叉反应 | HumanRatMouse |
| 应用 | WB |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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