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产品简介
| 英文名称 | Anti-MAPK14 Monoclonal Antibody |
| 别名 | CSBP;CSBP1;CSBP2;CSPB1;EXIP;Mxi2;p38;p38ALPHA;PRKM14;PRKM15;RK;SAPK2A |
| 宿主 | Mouse |
| 稀释比例 | WB 1:500. |
| Gene ID | 41kDa |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | Q16539 |
| 蛋白分子量 | 40kDa |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 亚细胞定位 | Cytoplasm Nucleus |
| 免疫原 | Purified recombinant human MAPK14P protein fragments expressed in E.coli. |
| 亚型 | IgG1 |
| 性状 | 液体 |
| 纯化方法 | Affinity purification |
| 克隆号 | 5A1-C5-F11 |
| 背景资料 | The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. |
| 克隆类型 | Monoclonal Antibody |
| 交叉反应 | HumanMonkeyRatMouse |
| 应用 | WB |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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