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产品简介
英文名称 | Anti-TNFRSF10B Monoclonal Antibody |
别名 | TNFRSF10B;CD262;DR5;KILLER;KILLER/DR5;TRAIL-R2;TRAILR2;TRICK2;TRICK2A;TRICK2B;TRICKB;ZTNFR9;TNF receptor superfamily member 10b |
宿主 | Mouse |
稀释比例 | WB 1:2000. |
Gene ID | 8795 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | O14763 |
储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
蛋白分子量 | 12/45/48kDa |
亚细胞定位 | Membrane Single-pass type I membrane protein |
免疫原 | Purified recombinant human TNFRSF10B protein fragments expressed in E.coli. |
亚型 | IgG2b |
性状 | 液体 |
纯化方法 | Affinity purification |
克隆号 | 4G12-F5-E9 |
背景资料 | The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein.Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene. |
克隆类型 | Monoclonal Antibody |
交叉反应 | Human |
应用 | WB |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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