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产品简介
| 英文名称 | Anti-ALDH2 Monoclonal Antibody |
| 别名 | ALDH-E2;ALDHI;ALDM |
| 宿主 | Mouse |
| 稀释比例 | WB 1:1000. |
| Gene ID | 217 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | P05091 |
| 蛋白分子量 | 56kDa |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 亚细胞定位 | Mitochondrion matrix |
| 免疫原 | Purified recombinant human ALDH2 protein fragments expressed in E.coli |
| 亚型 | IgG1 |
| 性状 | 液体 |
| 纯化方法 | Affinity purification |
| 克隆号 | 8D4-D6-D11 |
| 背景资料 | This protein belongs to the aldehyde dehydrogenase family of proteins.Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism.Two major liver isoforms of aldehyde dehydrogenase,cytosolic and mitochondrial,can be distinguished by their electrophoretic mobilities,kinetic properties,and subcellular localizations.Most Caucasians have two major isozymes,while approximately 50% of Orientals have the cytosolic isozyme but not the mitochondrial isozyme.A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of a catalytically active form of the mitochondrial isozyme.The increased exposure to acetaldehyde in individuals with the catalytically inactive form may also confer greater susceptibility to many types of cancer.This gene encodes a mitochondrial isoform,which has a low Km for acetaldehydes,and is localized in mitochondrial matrix.Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq,Mar 2011] |
| Public Immunogen Range | Purified recombinant human ALDH2 protein fragments expressed in E.coli |
| 克隆类型 | Monoclonal Antibody |
| 交叉反应 | HumanHamsterMonkeyRatMouse |
| 应用 | WB |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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