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产品简介
| 英文名称 | Anti-STAT3 Monoclonal Antibody |
| 别名 | ADMIO;ADMIO1;APRF;HIES;ADMIO;APRF;HIES |
| 宿主 | Mouse |
| 稀释比例 | WB 1:1000. |
| Gene ID | 6774 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | P40763 |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 蛋白分子量 | 83/88kDa |
| 亚细胞定位 | Cytoplasm Nucleus |
| 免疫原 | Purified recombinant human STAT3 protein fragments expressed in E.coli |
| 亚型 | IgG1 |
| 性状 | 液体 |
| 纯化方法 | Affinity purification |
| 克隆号 | 4C8-1C9-H8 |
| 背景资料 | The protein encoded by this gene is a member of the STAT protein family.In response to cytokines and growth factors,STAT family members are phosphorylated by the receptor associated kinases,and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators.This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs,EGF,IL5,IL6,HGF,LIF and BMP2.This protein mediates the expression of a variety of genes in response to cell stimuli,and thus plays a key role in many cellular processes such as cell growth and apoptosis.The small GTPase Rac1 has been shown to bind and regulate the activity of this protein.PIAS3 protein is a specific inhibitor of this protein.Three alternatively spliced transcript variants encoding distinct isoforms have been described.[provided by RefSeq,Jul 2008] |
| Public Immunogen Range | Purified recombinant human STAT3 protein fragments expressed in E.coli |
| 克隆类型 | Monoclonal Antibody |
| 交叉反应 | HumanHamsterMonkeyRatMouse |
| 应用 | WB |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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