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产品简介
| 英文名称 | Anti-ZAP70 Monoclonal Antibody |
| 别名 | ADMIO2;IMD48;SRK;STCD;STD;TZK;ZAP-70;SRK;STCD;STD;TZK;ZAP-70 |
| 宿主 | Mouse |
| 稀释比例 | WB 1:1000. |
| Gene ID | 7535 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | P43403 |
| 蛋白分子量 | 70kDa |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 亚细胞定位 | Cell membrane Cytoplasm Peripheral membrane protein |
| 免疫原 | Purified recombinant human ZAP70 protein fragments expressed in E.coli. |
| 亚型 | IgG2b |
| 性状 | 液体 |
| 纯化方法 | Affinity purification |
| 克隆号 | 4B2-C1-H3 |
| 背景资料 | This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| 克隆类型 | Monoclonal Antibody |
| 交叉反应 | Human |
| 应用 | WBIP |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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