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产品简介
| 英文名称 | Anti-SMARCA4 Monoclonal Antibody |
| 别名 | BAF190;BAF190A;BRG1;CSS4;hSNF2b;MRD16;RTPS2;SNF2;SNF2L4;SNF2LB;SWI2 |
| 宿主 | Mouse |
| 稀释比例 | WB 1:1000. ICC 1:50. |
| Gene ID | 6597 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | P51532 |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 蛋白分子量 | 185kDa |
| 亚细胞定位 | Nucleus |
| 免疫原 | Purified recombinant human SMARCA4 protein fragments expressed in E.coli. |
| 亚型 | IgG1 |
| 性状 | 液体 |
| 纯化方法 | Affinity purification |
| 克隆号 | 6D7-F7-B6 |
| 背景资料 | The protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila.Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes.The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI,which is required for transcriptional activation of genes normally repressed by chromatin.In addition, this protein can bind BRCA1,as well as regulate the expression of the tumorigenic protein CD44.Mutations in this gene cause rhabdoid tumor predisposition syndrome type 2.Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq,May 2012] |
| 克隆类型 | Monoclonal Antibody |
| 交叉反应 | HumanMouse |
| 应用 | WBIPIF |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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