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产品简介
| 英文名称 | Anti-ERCC1 Monoclonal Antibody |
| 别名 | COFS4;RAD10;UV20 |
| 宿主 | Mouse |
| 稀释比例 | WB 1:1000. |
| Gene ID | 2067 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | P07992 |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 蛋白分子量 | 33kDa |
| 亚细胞定位 | Cytoplasm Nucleus |
| 免疫原 | Purified recombinant human ERCC1 protein fragments expressed in E.coli. |
| 亚型 | IgG2b |
| 性状 | 液体 |
| 纯化方法 | Affinity purification |
| 克隆号 | 7F6-2A10-E8 |
| 背景资料 | The product of this gene functions in the nucleotide excision repair pathway,and is required for the repair of DNA lesions such as those induced by UV light or formed by electrophilic compounds including cisplatin.The encoded protein forms a heterodimer with the XPF endonuclease (also known as ERCC4),and the heterodimeric endonuclease catalyzes the 5' incision in the process of excising the DNA lesion.The heterodimeric endonuclease is also involved in recombinational DNA repair and in the repair of inter-strand crosslinks.Mutations in this gene result in cerebrooculofacioskeletal syndrome,and polymorphisms that alter expression of this gene may play a role in carcinogenesis.Multiple transcript variants encoding different isoforms have been found for this gene.The last exon of this gene overlaps with the CD3e molecule,epsilon associated protein gene on the opposite strand.[provided by RefSeq,Oct 2009] |
| Public Immunogen Range | Purified recombinant human ERCC1 protein fragments expressed in E.coli. |
| 克隆类型 | Monoclonal Antibody |
| 交叉反应 | Human |
| 应用 | WB |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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