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产品简介
| 英文名称 | Anti-AIFM1 Monoclonal Antibody |
| 别名 | AIF;CMT2D;CMTX4;COWCK;COXPD6;DFNX5;NADMR;NAMSD;PDCD8 |
| 宿主 | Mouse |
| 稀释比例 | WB 1:1000. ICC 1:200. |
| Gene ID | 9131 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | O95831 |
| 蛋白分子量 | 67kDa |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 亚细胞定位 | Cytoplasm Mitochondrion inner membrane Mitochondrion intermembrane space Nucleus perinuclear region |
| 免疫原 | Purified recombinant human AIFM1 protein fragments expressed in E.coli. |
| 亚型 | IgG2a |
| 性状 | 液体 |
| 纯化方法 | Affinity purification |
| 克隆号 | 8H1-B10-A12 |
| 背景资料 | This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells, and it is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it affects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Mutations in this gene cause combined oxidative phosphorylation deficiency 6, which results in a severe mitochondrial encephalomyopathy. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 10. |
| 克隆类型 | Monoclonal Antibody |
| 交叉反应 | Human |
| 应用 | WBIF |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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