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产品简介
英文名称 | Anti-Wnt3 Monoclonal Antibody |
别名 | INT4;TETAMS |
宿主 | Mouse |
稀释比例 | WB 1:1000. |
Gene ID | 7473 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | P56703 |
蛋白分子量 | 40kDa |
储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
亚细胞定位 | Secreted extracellular matrix extracellular space |
免疫原 | Purified recombinant human Wnt3 protein fragments expressed in E.coli. |
亚型 | lgG1 |
性状 | 液体 |
纯化方法 | Affinity purification |
克隆号 | 4F11-H1-F4 |
背景资料 | The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 98% amino acid identity to mouse Wnt3 protein, and 84% to human WNT3A protein, another WNT gene product. The mouse studies show the requirement of Wnt3 in primary axis formation in the mouse. Studies of the gene expression suggest that this gene may play a key role in some cases of human breast, rectal, lung, and gastric cancer through activation of the WNT-beta-catenin-TCF signaling pathway. This gene is clustered with WNT15, another family member, in the chromosome 17q21 region. |
Public Immunogen Range | Purified recombinant human Wnt3 protein fragments expressed in E.coli. |
克隆类型 | Monoclonal Antibody |
交叉反应 | Transfected |
应用 | WB |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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