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产品简介
英文名称 | Anti-RELA Monoclonal Antibody |
别名 | NFKB3;p65;NFkB p65 |
宿主 | Mouse |
稀释比例 | WB 1:500-2000. IP 1:200. IF 1:100-200. IHC 1:200-500. |
Gene ID | 5970 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | Q04206 |
储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
蛋白分子量 | 59/60kDa |
亚细胞定位 | Cytoplasm Nucleus |
免疫原 | Recombinant Protein |
亚型 | IgG1 |
性状 | 液体 |
纯化方法 | Saturated ammonium sulfate precipitation |
克隆号 | 5G6 |
背景资料 | NFkB p65 is ubiquitinated leading to its proteosomal degradation, which is required for termination of the NFkB response. Phosphorylation of NFkB p65 on S536 stimulates acetylation of K310 by CBP, enhancing transcriptional activity. NFkB p65 is also acetylated at K122, enhancing DNA binding and impairing the interaction with NFKBIA. The protein is deacetylated by HDAC3. Invasion of a host by a pathogen is frequently associated with the activation of NF-kB, which coordinates various aspects of immune function required for resistance to infection. |
Public Immunogen Range | Recombinant Protein |
克隆类型 | Monoclonal Antibody |
交叉反应 | HumanRatMouse |
应用 | WBIHCIFIP |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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