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产品简介
英文名称 | Anti-CTNNB1 Monoclonal Antibody |
别名 | CTNNB;MRD19;armadillo;β-Catenin;Cadherin associated protein |
宿主 | Mouse |
稀释比例 | WB 1:1000-2000. IHC 1:200-500. |
Gene ID | 1499 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | P35222 |
储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
蛋白分子量 | 85kDa |
亚细胞定位 | Cell junction Cell membrane Cytoplasm Nucleus adherens junction centrosome cytoskeleton microtubule organizing center spindle pole |
免疫原 | Recombinant Protein |
亚型 | IgG1 |
性状 | 液体 |
纯化方法 | Saturated ammonium sulfate precipitation |
克隆号 | 4F2 |
背景资料 | The distinct peripheral cytosolic proteins, alpha, beta and gamma catenin (102, 94 and 86 kDa) are found in many tissues and bind to the conserved cytoplasmic tail domain of the cell adhesion cadherins. Catenins link E cadherin to other integral membrane or cytoplasmic proteins and are modulated by Wnt1 proto oncogene. The central core region of beta catenin is involved in mediation of cadherin catenin complex interaction with EGFR. Beta-Catenin-mediated signalling is involved at several stages of vertebrate neural development. |
Public Immunogen Range | Recombinant Protein |
克隆类型 | Monoclonal Antibody |
交叉反应 | HumanRatMouse |
应用 | WBIHC |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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