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产品简介
| 英文名称 | Anti-STAT3 Monoclonal Antibody |
| 别名 | ADMIO;ADMIO1;APRF;HIES;ADMIO;APRF;HIES |
| 宿主 | Mouse |
| 稀释比例 | WB 1:1000-2000. IHC 1:100-200. |
| Gene ID | 6774 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | P40763 |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 蛋白分子量 | 83/88kDa |
| 亚细胞定位 | Cytoplasm Nucleus |
| 免疫原 | Recombinant Protein |
| 亚型 | IgG1 |
| 性状 | 液体 |
| 纯化方法 | Saturated ammonium sulfate precipitation |
| 克隆号 | 3F4 |
| 背景资料 | Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF, LEP and other growth factors. Once activated, recruits coactivators, such as NCOA1 or MED1, to the promoter region of the target gene . May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the interleukin-6 (IL-6)-responsive elements identified in the promoters of various acute-phase protein genes. Activated by IL31 through IL31RA. Involved in cell cycle regulation by inducing the expression of key genes for the progression from G1 to S phase, such as CCND1. Mediates the effects of LEP on melanocortin production, body energy homeostasis and lactation (By similarity). May play an apoptotic role by transctivating BIRC5 expression under LEP activation . Cytoplasmic STAT3 represses macroautophagy by inhibiting EIF2AK2/PKR activity. |
| Public Immunogen Range | Recombinant Protein |
| 克隆类型 | Monoclonal Antibody |
| 交叉反应 | HumanRatMouse |
| 应用 | WBIHC |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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