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产品简介
英文名称 | Anti-SFPQ Polyclonal Antibody |
别名 | POMP100;PPP1R140;PSF |
宿主 | Rabbit |
稀释比例 | WB 1:500-1000. IHC 1:50-100. IF 1:50-100. |
Gene ID | 6421 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | P23246 |
蛋白分子量 | 76kDa |
储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
亚细胞定位 | Cytoplasm Nucleus matrix |
免疫原 | Recombinant protein of human SFPQ |
亚型 | IgG |
性状 | 液体 |
纯化方法 | Affinity purification |
背景资料 | SFPQ, also named PSF, encodes a nuclear factor implicated in the splicing and regulation of gene expression. SFPQ probably forms a heteromer with NONO and participates in DNA pairing and DNA break repair program. Very recently SFPQ was identified as a downstream target of tau, complete nuclear depletion and cytoplasmic accumulation of SFPQ were shown in the neurons and astrocytes of brains with Alzheimer's disease (AD), more strikingly, reduced SFPQ levels may progress together with tau pathology, these observation strongly suggests the important role of SFPQ pathology in neurodegenerative diseases including AD. SFPQ protein may appears as 47 kDa, 52 kDa or 100 kDa molecules in various cell types. Catalog# 15585-1-AP is a rabbit polyclonal antibody raised against the N-terminal of human SFPQ. |
Public Immunogen Range | Recombinant protein of human SFPQ |
克隆类型 | Polyclonal Antibody |
交叉反应 | HumanRatMouse |
应用 | WBIFIHC |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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