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产品名称
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产品简介
英文名称 | Anti-UPF1 Polyclonal Antibody |
别名 | HUPF1;NORF1;RENT1;pNORF1;smg-2 |
宿主 | Rabbit |
稀释比例 | WB 1:500-2000. IF 1:50-200. |
Gene ID | 5976 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | Q92900 |
蛋白分子量 | 124kDa |
储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
亚细胞定位 | Cytoplasm Nucleus P-body |
免疫原 | A synthetic peptide of human UPF1 |
亚型 | IgG |
性状 | 液体 |
纯化方法 | Affinity purification |
背景资料 | This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping. Use of multiple polyadenylation sites has been noted for this gene. Alternative splicing results in multiple transcript variants. |
Public Immunogen Range | A synthetic peptide of human UPF1 |
克隆类型 | Polyclonal Antibody |
交叉反应 | HumanRatMouse |
应用 | WBIF |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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