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产品简介
英文名称 | Anti-EIF4G2 Polyclonal Antibody |
别名 | AAG1;DAP5;NAT1;P97 |
宿主 | Rabbit |
稀释比例 | WB 1:500-1000. IHC 1:100-200. |
Gene ID | 1982 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | P78344 |
蛋白分子量 | 102kDa |
储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
亚细胞定位 | Cytosol |
免疫原 | A synthetic peptide of human EIF4G2 |
亚型 | IgG |
性状 | 液体 |
纯化方法 | Affinity purification |
背景资料 | Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. The protein encoded by this gene shares similarity with the C-terminal region of eIF4G that contains the binding sites for eIF4A and eIF3; eIF4G, in addition, contains a binding site for eIF4E at the N-terminus. Unlike eIF4G, which supports cap-dependent and independent translation, this gene product functions as a general repressor of translation by forming translationally inactive complexes. In vitro and in vivo studies indicate that translation of this mRNA initiates exclusively at a non-AUG (GUG) codon. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. |
Public Immunogen Range | A synthetic peptide of human EIF4G2 |
克隆类型 | Polyclonal Antibody |
交叉反应 | HumanRatMouse |
应用 | WBIFIHC |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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