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产品简介
英文名称 | Anti-BAG2 Polyclonal Antibody |
别名 | BAG-2;dJ417I1.2 |
稀释比例 | WB 1:500-2000. IHC 1:50-200. IF 1:50-200. |
Gene ID | 9532 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | O95816 |
蛋白分子量 | 24kDa |
储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
亚细胞定位 | Cytoplasm Cytoskeleton Cytosol |
免疫原 | Recombinant protein of human BAG2 |
亚型 | IgG |
性状 | 液体 |
纯化方法 | Affinity purification |
背景资料 | BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. |
Public Immunogen Range | Recombinant protein of human BAG2 |
克隆类型 | Polyclonal Antibody |
交叉反应 | Human |
应用 | WBIFIHC |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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