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产品简介
英文名称 | Anti-UHRF1(N-term) Monoclonal Antibody |
别名 | hNP95;hUHRF1;huNp95;ICBP90;Np95;RNF106;TDRD22 |
宿主 | Mouse |
稀释比例 | WB 1:1000. |
Gene ID | 29128 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | Q96T88 |
蛋白分子量 | 90kDa |
储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
亚细胞定位 | Nucleus |
免疫原 | Purified recombinant human UHRF1 protein fragments expressed in E.coil. |
亚型 | IgG2b |
性状 | 液体 |
纯化方法 | Affinity purification |
克隆号 | 1H9-D3-E11 |
背景资料 | This gene encodes a member of a subfamily of RING-finger type E3 ubiquitin ligases. The protein binds to specific DNA sequences, and recruits a histone deacetylase to regulate gene expression. Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle. It plays a major role in the G1/S transition by regulating topoisomerase IIalpha and retinoblastoma gene expression, and functions in the p53-dependent DNA damage checkpoint. Multiple transcript variants encoding different isoforms have been found for this gene. |
Public Immunogen Range | Purified recombinant human UHRF1 protein fragments expressed in E.coil. |
克隆类型 | Monoclonal Antibody |
交叉反应 | HumanMouse |
应用 | WB |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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