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产品简介
| 英文名称 | Anti-SMC1A(C-term) Monoclonal Antibody |
| 别名 | CDLS2;DXS423E;SB1.8;SMC1;SMC1alpha;SMC1L1;SMCB |
| 宿主 | Mouse |
| 稀释比例 | WB 1:1000. IHC 1:100. |
| Gene ID | 8243 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | Q14683 |
| 蛋白分子量 | 143kDa |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 亚细胞定位 | Chromosome Nucleus centromere kinetochore |
| 免疫原 | Purified recombinant human SMC1A(C-term.) protein fragments expressed in E.coli. |
| 亚型 | IgG1 |
| 性状 | 液体 |
| 纯化方法 | Affinity purification |
| 克隆号 | 4C5-C8-A11 |
| 背景资料 | Proper cohesion of sister chromatids is a prerequisite for the correct segregation of chromosomes during cell division. The cohesin multiprotein complex is required for sister chromatid cohesion. This complex is composed partly of two structural maintenance of chromosomes (SMC) proteins, SMC3 and either SMC1L2 or the protein encoded by this gene. Most of the cohesin complexes dissociate from the chromosomes before mitosis, although those complexes at the kinetochore remain. Therefore, the encoded protein is thought to be an important part of functional kinetochores. In addition, this protein interacts with BRCA1 and is phosphorylated by ATM, indicating a potential role for this protein in DNA repair. This gene, which belongs to the SMC gene family, is located in an area of the X-chromosome that escapes X inactivation. [provided by RefSeq, Jul 2008] |
| Public Immunogen Range | Purified recombinant human SMC1A(C-term.) protein fragments expressed in E.coli. |
| 克隆类型 | Monoclonal Antibody |
| 交叉反应 | Human |
| 应用 | WBICC |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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