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产品简介
英文名称 | Anti-PDHA1 Monoclonal Antibody |
别名 | PDHA;PDHAD;PDHCE1A;PHE1A |
宿主 | Mouse |
稀释比例 | WB 1:1000. IHC 1:100. |
Gene ID | 5160 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | P08559 |
蛋白分子量 | 43kDa |
储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
亚细胞定位 | Cytoplasm |
免疫原 | Purified recombinant human PDHA1 protein fragments expressed in E.coli. |
亚型 | IgG1 |
性状 | 液体 |
纯化方法 | Affinity purification |
克隆号 | 3H2-F8-B5 |
背景资料 | The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 alpha 1 subunit containing the E1 active site, and plays a key role in the function of the PDH complex. Mutations in this gene are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
克隆类型 | Monoclonal Antibody |
交叉反应 | HumanMouse |
应用 | WBICC |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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