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产品简介
| 英文名称 | Anti-ACLY Monoclonal Antibody |
| 别名 | ACL;ATPCL;CLATP;ATP-Citrate Lyase |
| 宿主 | Mouse |
| 稀释比例 | WB 1:1000. IHC 1:150. |
| Gene ID | 47 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | P53396 |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 蛋白分子量 | 91/121kDa |
| 亚细胞定位 | Cytoplasm |
| 免疫原 | Purified recombinant human ATP-Citrate Lyase protein fragments expressed in E.coli. |
| 亚型 | IgG2a |
| 性状 | 液体 |
| 纯化方法 | Affinity purification |
| 克隆号 | 3D9-E9-H8 |
| 背景资料 | ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Two transcript variants encoding distinct isoforms have been identified for this gene. |
| 克隆类型 | Monoclonal Antibody |
| 交叉反应 | HumanMonkeyMouse |
| 应用 | WBFCICC |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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