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产品简介
英文名称 | Anti-CCND2 Monoclonal Antibody |
别名 | KIAK0002;MPPH3;Cyclin D2 |
宿主 | Mouse |
稀释比例 | WB 1:1000. |
Gene ID | 894 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | P30279 |
蛋白分子量 | 38kDa |
储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
亚细胞定位 | Cytoplasm Membrane Nucleus |
免疫原 | Purified recombinant human CCND2 protein fragments expressed in E.coli. |
亚型 | IgG2b |
性状 | 液体 |
纯化方法 | Affinity purification |
克隆号 | 6E11-G6-F5 |
背景资料 | The protein encoded by this gene belongs to the highly conserved cyclin family,whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle.Cyclins function as regulators of CDK kinases.Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event.This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition.This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb.Knockout studies of the homologous gene in mouse suggest the essential roles of this gene in ovarian granulosa and germ cell proliferation.High level expression of this gene was observed in ovarian and testicular tumors.[provided by RefSeq,Oct 2008] |
克隆类型 | Monoclonal Antibody |
交叉反应 | Human |
应用 | WB |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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