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产品简介
英文名称 | Anti-Rad51 Monoclonal Antibody |
别名 | BRCC5;FANCR;HRAD51;HsRad51;HsT16930;MRMV2;RAD51A;RECA |
宿主 | Mouse |
稀释比例 | WB 1:1000. |
Gene ID | 5888 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | Q06609 |
储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
蛋白分子量 | 37/26/31kDa |
亚细胞定位 | Cytoplasm Mitochondrion matrix Nucleus |
免疫原 | Recombinant protein of human Rad51. |
亚型 | IgG2a |
性状 | 液体 |
纯化方法 | Affinity purification |
克隆号 | 4H10-G5-H4 |
背景资料 | The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with the ssDNA-binding protein RPA and RAD52, and it is thought to play roles in homologous pairing and strand transfer of DNA. This protein is also found to interact with BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis. Multiple transcript variants encoding different isoforms have been found for this gene. |
Public Immunogen Range | Recombinant protein of human Rad51. |
克隆类型 | Monoclonal Antibody |
交叉反应 | HumanMonkeyRatMouse |
应用 | WB |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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