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产品简介
英文名称 | Anti-BRAF Monoclonal Antibody |
别名 | B-raf;B-RAF1;BRAF1;NS7;RAFB1;B-RAF1;BRAF1;NS7;RAFB1 |
宿主 | Mouse |
稀释比例 | WB 1:1000. |
Gene ID | 673 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | P15056 |
储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
蛋白分子量 | 84kDa |
亚细胞定位 | Cell membrane Cytoplasm Nucleus |
免疫原 | Purified recombinant human BRAF protein fragments expressed in E.coli. |
亚型 | IgG2a |
性状 | 液体 |
纯化方法 | Affinity purification |
克隆号 | 4E1-E1-F9 |
背景资料 | This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene. |
克隆类型 | Monoclonal Antibody |
交叉反应 | HumanMouse |
应用 | WB |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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