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| 英文名称 | Anti-CCNH Monoclonal Antibody |
| 别名 | CAK;CycH;p34;p37;Cyclin H |
| 宿主 | Mouse |
| 稀释比例 | WB 1:1000. |
| Gene ID | 902 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | P51946 |
| 蛋白分子量 | 38kDa |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 亚细胞定位 | Nucleus |
| 免疫原 | Purified recombinant human CCNH protein fragments expressed in E.coli. |
| 亚型 | IgG2b |
| 性状 | 液体 |
| 纯化方法 | Affinity purification |
| 克隆号 | 4E11-G2-D7 |
| 背景资料 | The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with CDK7 kinase and ring finger protein MAT1. The kinase complex is able to phosphorylate CDK2 and CDC2 kinases, thus functions as a CDK-activating kinase (CAK). This cyclin and its kinase partner are components of TFIIH, as well as RNA polymerase II protein complexes. They participate in two different transcriptional regulation processes, suggesting an important link between basal transcription control and the cell cycle machinery. A pseudogene of this gene is found on chromosome 4. Alternate splicing results in multiple transcript variants.[ |
| 克隆类型 | Monoclonal Antibody |
| 交叉反应 | Human |
| 应用 | WBIP |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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