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产品简介
英文名称 | Anti-SAFB Monoclonal Antibody |
别名 | HAP;HET;SAB-B1;SAF-B;SAF-B1;SAFB1 |
宿主 | Mouse |
稀释比例 | WB 1:1000. IHC 1:200. |
Gene ID | 6294 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | Q15424 |
储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
蛋白分子量 | 95/103kDa |
亚细胞定位 | Nucleus |
免疫原 | Purified recombinant human SAFB protein fragments expressed in E.coli. |
亚型 | IgG1 |
性状 | 液体 |
纯化方法 | Affinity purification |
克隆号 | 2E8-E2-G6 |
背景资料 | This gene encodes a DNA-binding protein which has high specificity for scaffold or matrix attachment region DNA elements (S/MAR DNA). This protein is thought to be involved in attaching the base of chromatin loops to the nuclear matrix but there is conflicting evidence as to whether this protein is a component of chromatin or a nuclear matrix protein. Scaffold attachment factors are a specific subset of nuclear matrix proteins (NMP) that specifically bind to S/MAR. The encoded protein is thought to serve as a molecular base to assemble a 'transcriptosome complex' in the vicinity of actively transcribed genes. It is involved in the regulation of heat shock protein 27 transcription, can act as an estrogen receptor co-repressor and is a candidate for breast tumorigenesis. This gene is arranged head-to-head with a similar gene whose product has the same functions. Multiple transcript variants encoding different isoforms have been found for this gene. |
克隆类型 | Monoclonal Antibody |
交叉反应 | Human |
应用 | WBICC |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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